Scarred Brains or Shiny Statistics: The Perils of CCA

Posted on Categories Discover Magazine

A paper in PNAS got some attention on Twitter recently. It’s called Childhood trauma history is linked to abnormal brain connectivity in major depression and in it, the authors Yu et al. report finding (as per the Significance Statement)
A dramatic primary association of brain resting-state network (RSN) connectivity abnormalities with a history of childhood trauma in major depressive disorder (MDD).
The authors go on to note that even though “the brain imaging took place decades after trauma

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